Research Information System
Özen A. (Executive), Duruer K.
TUBITAK Project, 2021 - 2022
Endometrial cancer, which is the most common cancer of the female genital system, is an
important health problem, especially in older women. Although the stage of the disease at the
time of diagnosis is prognostically important, the primary treatment is curative surgery in the
presence of both early stage and locally advanced disease. Radiotherapy is the primary
treatment for patients who cannot be operated on due to different medical reasons. In patients
who cannot be operated on due to medical reasons, brachytherapy treatment is applied only
in the presence of limited early-stage disease in the uterus, and in the presence of
intracavitary parametrial invasion, intracavitary and interstitial. When the applicators available
in the market are examined, 2 or 3 rigid tandems of different angles and sizes are placed into
the uterus through which the radioactive source will pass, and it is very difficult to apply and
position. In addition, because the applicators are brought from abroad, their costs are quite
high. In this project, we aimed to develop an intrauterine 3-channel high-dose rapid
brachytherapy applicator prototype, which can be placed as a single piece combined with the
multi-channel cylinder applicator, which can be placed more easily and cost-effectively in
patients diagnosed with endometrial cancer compared to its counterparts in the current
market.