Research Information System
İstanbullu Ö. B., Akdoğan G.(Executive)
Project Supported by Higher Education Institutions, BAP Research Project, 2015 - 2017
Magnetic Resonance Imaging (MRI) device is preferred in comparison with the other diagnostic devices due to being harmless to human health and high resolution image quality. However, usage is avoided owing to the apprehension of whatsoever implant inside the body might be MRI incompatible. Electrically conductive and ferromagnetic featured medical aimed biomaterials have electromagnetic interaction potential with quite strong static magnetic field, magnetic radio frequency pulses and gradient magnetic fields inside the MRI environment. Healthy tissues surrounding biomaterials suffer damage due to the fact that physical effects of mentioned interaction such as temperature increase, magnetic force and torque formation on the MRI incompatible material. In an attempt to distinguish implants which are MRI compatible, doing compatibility/safety tests at the production phase will overcome the problem. In this study, firstly electrical conductivity level of different organs in the body is determined then conditions close to body circumstances are simulated by Sim4Life packaged software in computer environment. Electromagnetic energy distribution and heating effect of material is examined by creating phantom and materials in simulation environment. 21 individual test samples which are 3 different designed and have 7 different material content are used to analyse behavior of material inside real MRI environment. RF induced heating and deformation level of MR images of samples are examined in 4 different MRI conditions which are “Axial and Sagittal T1 Gradient Echo” and “Axial and Sagittal T2 Turbo Spin Echo” imaging sequences. ASTM standards are used as reference for determining MRI compatibility level of test samples.
Keywords: MRI Compatible Biomaterials, Medical Implant, Magnetic Resonance Imaging, RF Induced Heating, MRI Compatibility, MRI Safety