A severe course of serogroup W meningococcemia in a patient with infantile nephropathic cystinosis.


BOZAN G., KILIÇ Ö., ÇETİN N., KILIÇ YILDIRIM G., Ulukapi H. B., Iseri Nepesov M., ...Daha Fazla

Human vaccines & immunotherapeutics, cilt.16, sa.11, ss.2787-2788, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 11
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1080/21645515.2020.1742508
  • Dergi Adı: Human vaccines & immunotherapeutics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.2787-2788
  • Anahtar Kelimeler: Invasive meningococcal disease, neisseria meningitidis, serogroup W, MenW, cystinosis, DISEASE
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

We present a 9-month old boy with cystinosis admitted to our hospital with the complaints of vomiting, diarrhea and seizure. While he was hospitalized in a pediatric intensive care unit due to worsening of his signs related to cystinosis, within hours, he suffered complications of septic shock, acute renal failure, and disseminated intravascular coagulation, due to invasive Neisseria meningitidis serogroup W disease. Our patient is the first reported case of invasive meningococcal disease with cystinosis. Clinicians should consider that the unexpected and serious clinical findings of invasive meningococcal disease can mimic and/or masquerade as other metabolic diseases. Vaccination strategies, according to serogroup epidemiology and age distribution, should be implemented for the prevention of meningococcal infections.