Oxidant and antioxidant status in neonatal proven and clinical sepsis according to selenium status

Asci A., Surmeli-Onay Ö., Erkekoglu P., YİĞİT Ş., YURDAKÖK M., Kocer-Gumusel B.

PEDIATRICS INTERNATIONAL, cilt.57, sa.6, ss.1131-1137, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/ped.12698
  • Dergi Adı: PEDIATRICS INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1131-1137
  • Anahtar Kelimeler: antioxidant enzyme, clinical sepsis, oxidative stress, proven sepsis, selenium, selenoenzyme, SYSTEMIC INFLAMMATORY RESPONSE, SEPTIC SHOCK, GLUTATHIONE-PEROXIDASE, LIPID-PEROXIDATION, OXIDATIVE STRESS, PLASMA, THIOREDOXIN, MORTALITY
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

BackgroundSelenium is a trace element required for the functioning of the immune system. Neonatal sepsis is a serious condition leading to morbidity and mortality in neonates worldwide. The purpose of this study was to measure selenium and plasma selenoprotein P (SePP), selenoenzyme activity, and alterations in oxidant/antioxidant status with immune biomarkers in neonates with clinical (n=27) and proven neonatal sepsis (n=25).