The Effect of Intracameral Triamcinolone Acetonide Application on Postoperative Inflammation and Intraocular Pressure After Phacoemulsification

Şimşek T., Tekin K.

Glokom Katarakt, cilt.17, sa.3, ss.118-123, 2022 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.37844/glauc.cat.2022.17.19
  • Dergi Adı: Glokom Katarakt
  • Derginin Tarandığı İndeksler: EBSCO Education Source, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.118-123
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Purpose: To evaluate effects of intracameral 2mg/0.1ml triamcinolone acetonide administered at the end of uncomplicated phacoemulsification surgery on postoperative inflammation and intraocular pressure (IOP). Materials and Methods: This prospective study included 50 eyes of 50 patients who underwent uncomplicated phacoemulsification surgery. At the end of surgery, 2 mg/0.1ml of triamcinolone was injected into the anterior chamber in 26 eyes (Group A) while balanced salt solution was administered to 24 eyes as placebo (Group B). Topical prednisolone acetate 1% treatment was given to the Group B postoperatively while Group A did not receive any topical steroid therapy. Best corrected visual acuity, spherical and cylindrical refraction and IOP values as well as degree of corneal edema and anterior chamber reaction were compared between groups on the postoperative day 1and week 1. Results: There was no significant difference in IOP measured on postoperative day and week 1 between groups (p>0.05). In both groups, mean IOP was higher on postoperative day 1 than preoperative IOP. The IOP increase was 1.6±6.0 mmHg in group A and 4.1±6.7 mmHg in group B on postoperative day 1. There was no significant difference in IOP change on postoperative day 1 between groups (p=0.120). No significant difference was found in degree of corneal edema and anterior chamber cell on postoperative day 1 and week 1 between groups (p>0.05). Conclusion: After uncomplicated cataract surgery, 2mg/0.1ml intracameral triamcinolone injection was found to be as effective as topical 1% prednisolone acetate in controlling postoperative inflammation.