Immunotherapy in all aspects


Hanci D., Sahin E., MULUK N. B., CİNGİ C.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, cilt.273, sa.6, ss.1347-1355, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 273 Sayı: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s00405-015-3553-5
  • Dergi Adı: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1347-1355
  • Anahtar Kelimeler: Immunotherapy, Subcutaneous immunotherapy (SCIT), Sublingual immunotherapy (SLIT), Effectiveness, Safety, GRASS-POLLEN IMMUNOTHERAPY, ALLERGEN-SPECIFIC IMMUNOTHERAPY, HOUSE-DUST MITE, SUBLINGUAL-SWALLOW IMMUNOTHERAPY, TERM CLINICAL-EFFICACY, T-REGULATORY CELLS, DOUBLE-BLIND, MESSENGER-RNA, FOLLOW-UP, DERMATOPHAGOIDES-PTERONYSSINUS
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Allergen immunotherapy is a form of long-term treatment that decreases symptoms for many people with allergic rhinitis, allergic asthma, conjunctivitis (eye allergy) or stinging insect allergy. In this review, we presented the important topics in immunotherapy. The important aspects of immunotherapy are considered to be "ImmunologA +/- cal responses to immunotherapy"; "The principal types of immunotherapy"; "Effectiveness"; "Indications"; "Contraindications"; "Allergen immunotherapy in children"; "Safety"; and "Anaphylactic reactions after immunotherapy". The principal types of immunotherapy are subcutaneous immunotherapy (SCIT) and sublingual immunotherapy. Both of them can be used in indicated cases. When using SCIT, physicians must be more careful because of reported rare fatal cases. The risks and benefits of continuing allergen immunotherapy in patients who have experienced severe systemic reactions should be carefully considered.