Glomerulonephritis and Coombs-positive hemolytic anemia mimicking scleroderma renal crisis in an overlap of systemic lupus erythematosus and diffuse systemic sclerosis


Taylan A., Tekin E., Engin B.

Rheumatology International, cilt.40, sa.5, ss.785-789, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 40 Sayı: 5
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1007/s00296-019-04471-w
  • Dergi Adı: Rheumatology International
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.785-789
  • Anahtar Kelimeler: Systemic sclerosis and systemic lupus erythematosus overlap, Glomerulonephritis, Hemolytic anemia, Scleroderma renal crisis, CLASSIFICATION CRITERIA, ANTIBODY, DISEASE
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

© 2019, Springer-Verlag GmbH Germany, part of Springer Nature.Systemic sclerosis (SSc) may overlap frequently with other rheumatic diseases, including systemic lupus erythematosus (SLE), which can require high-dose steroids depending on the clinical presentation. We present a case involving this overlap in which the patient concomitantly developed lupus nephritis and Coombs (+) hemolytic anemia, which was confused with scleroderma renal crisis. In this condition, assessing for lupus nephritis with timely renal biopsy and lupus serology can aid in guiding the appropriate treatment. We discuss the clinical features and challenging management of this case with a review of the English-language literature for SSc and SLE overlap with glomerulonephritis.