IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme

---

Atıf İçin Kopyala

Kalkan R., Atli E. I., Ozdemir M., Ciftci E., Aydin H. E., ARTAN S., ...Daha Fazla

GENE, cilt.554, sa.1, ss.81-86, 2015 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 554 Sayı: 1
• Basım Tarihi: 2015
• Doi Numarası: 10.1016/j.gene.2014.10.027
• Dergi Adı: GENE
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.81-86
• Anahtar Kelimeler: Primary glioblastoma, IDH1 mutation, MGMT methylation, MS-HRM, CODON 132 MUTATION, PROMOTER METHYLATION, SURVIVAL, GLIOMAS
• Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Purpose: To establish the frequency of IDH1 mutations and MGMT methylation in primary glioblastomas. Experimental design: We screened primary glioblastoma multiforme (GBM) in a population-based study for IDH1 mutations and MGMT methylation and correlated them with clinical data.