The effect of leptin and resveratrol on JAK/STAT pathways and Sirt-1 gene expression in the renal tissue of ischemia//reperfusion induced rats

Erkasap, S.; ERKASAP, NİLÜFER; Bradford, B.; Mamedova, L.; UYSAL, ONUR; Ozkurt, METE; Ozkurt, R.; Kutlay, O.; Bayram, B.

doi:10.4149/bll_2017_086

The effect of leptin and resveratrol on JAK/STAT pathways and Sirt-1 gene expression in the renal tissue of ischemia//reperfusion induced rats

Atıf İçin Kopyala

Erkasap S., ERKASAP N., Bradford B., Mamedova L., UYSAL O., Ozkurt M., ...Daha Fazla

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.118, sa.8, ss.443-448, 2017 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 118 Sayı: 8
Basım Tarihi: 2017
Doi Numarası: 10.4149/bll_2017_086
Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.443-448
Anahtar Kelimeler: leptin, resveratrol, TNF-alpha, caspase 3, apoptosis, JAK-STAT PATHWAY, NF-KAPPA-B, ISCHEMIA/REPERFUSION INJURY, TNF-ALPHA, MYOCARDIAL ISCHEMIA/REPERFUSION, ISCHEMIA, CARDIOPROTECTION, PROTECTION, APOPTOSIS, FAILURE
Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Our study aimed to investigate the possible modifying effects of leptin and combined use of resveratrol on rat renal I/R injury and their relationship on signal pathways and apoptosis-related mechanisms.