Synthesis and analgesic activity of some triazoles and triazolothiadiazines

Turan-Zitouni G., Kaplancikli Z., Erol K., Kilic F. S.

FARMACO, cilt.54, sa.4, ss.218-223, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 4
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0014-827x(99)00016-6
  • Dergi Adı: FARMACO
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.218-223
  • Anahtar Kelimeler: tetrahydronaphthalentriazoles, triazaolothiadiazines, analgesic activity, ANTIFUNGAL ACTIVITY
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

The synthesis of some triazoles and triazolothiadiazines starting from (5,6,7,8-tetrahydronaphthalen-2-yl)oxyacetic acid is described. The chemical structure of the compounds were elucidated by analytical, IR, H-1 NMR and mass spectral studies. Some of the newly synthesized compounds were tested for analgesic activity and compounds 5b, 5c, and 5d exhibited promising analgesic activity. (C) 1999 Elsevier Science S.A. All rights reserved.