Evaluation of Pleiotropic Effects of Statins in Chronic Renal Failure Patients

ÖZKURT, SULTAN; SOYDAN, MEHMET; ŞAHİN, GARİP; BAL, CENGİZ; Alatas, İBRAHİM

doi:10.5262/tndt.2011.1002.06

Evaluation of Pleiotropic Effects of Statins in Chronic Renal Failure Patients

Atıf İçin Kopyala

ÖZKURT S., SOYDAN M., ŞAHİN G., BAL C., Alatas O.

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, cilt.20, sa.2, ss.150-155, 2011 (ESCI)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 2
Basım Tarihi: 2011
Doi Numarası: 10.5262/tndt.2011.1002.06
Dergi Adı: TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.150-155
Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

OBJECTIVES : Atherosclerosis is seen more frequently in patients with chronic renal failure (CRF) due to the oxidative stress, chronic inflammation and endothelial dysfunction. Besides lowering total and low density lipoprotein (LDL) cholesterol levels, statins also lower the frequency of cardiovascular incidents in patients with chronic renal failure by their pleiotropic effects. We aimed to investigate whether atorvastatin had pleiotropic effects in dialysis patients.