Effects of single and combined gabapentin use in elevated plus maze and forced swimming tests

Kılıç F. S., Ismailoglu S., Kaygısız B., Oner S.

ACTA NEUROPSYCHIATRICA, vol.26, pp.307-314, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26
  • Publication Date: 2014
  • Doi Number: 10.1017/neu.2014.17
  • Journal Name: ACTA NEUROPSYCHIATRICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.307-314
  • Keywords: antidepressant, anxiolytic, elevated plus maze, forced swimming test, gabapentin, NEUROPATHIC PAIN, ANXIETY, RATS, AMITRIPTYLINE, PREGABALIN, RECEPTORS, DISORDER, KETAMINE, DRUGS, MODEL
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background: Gabapentin, a third-generation antiepileptic drug, is a structural analogue of gamma-aminobutyric acid, which is an important mediator of central nervous system. There is clinical data indicating its effectiveness in the treatment of psychiatric illnesses such as bipolar disorder and anxiety disorders.