Effects of single and combined gabapentin use in elevated plus maze and forced swimming tests


Kılıç F. S., Ismailoglu S., Kaygısız B., Oner S.

ACTA NEUROPSYCHIATRICA, cilt.26, ss.307-314, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1017/neu.2014.17
  • Dergi Adı: ACTA NEUROPSYCHIATRICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.307-314
  • Anahtar Kelimeler: antidepressant, anxiolytic, elevated plus maze, forced swimming test, gabapentin, NEUROPATHIC PAIN, ANXIETY, RATS, AMITRIPTYLINE, PREGABALIN, RECEPTORS, DISORDER, KETAMINE, DRUGS, MODEL
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: Gabapentin, a third-generation antiepileptic drug, is a structural analogue of gamma-aminobutyric acid, which is an important mediator of central nervous system. There is clinical data indicating its effectiveness in the treatment of psychiatric illnesses such as bipolar disorder and anxiety disorders.