Update on local allergic rhinitis

Altintoprak N., Kar M., MULUK N. B., Oktemer T., Ipci K., Birdane L., ...Daha Fazla

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, cilt.87, ss.105-109, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 87
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.ijporl.2016.06.008
  • Dergi Adı: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.105-109
  • Anahtar Kelimeler: Local allergic rhinitis, Absence, Systemic atopy, Local production, Specific IgE, Antibodies, Mechanism, AZELASTINE NASAL SPRAY, INTRANASAL FLUTICASONE PROPIONATE, PERSISTENT NONALLERGIC RHINITIS, IDIOPATHIC RHINITIS, PROVOCATION TEST, OCULAR SYMPTOMS, MESSENGER-RNA, MAST-CELLS, EFFICACY, IGE
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

We here provide an update on the literature regarding local allergic rhinitis (LAR). In reviewing LAR, we have included an updated definition, classifications, mechanisms, comorbidities, and recommendations for diagnosis and treatment for LAR, as well as the defined research areas for future evidence-based studies. LAR is a localised nasal allergic response in the absence of systemic atopy characterised by local production of specific IgE (sIgE) antibodies, a TH2 pattern of mucosal cell infiltration during natural exposure to aeroallergens, and a positive nasal allergen provocation test response, with the release of inflammatory mediators. The localised allergic response of LAR is an important topic for the study of allergies. This review provides an update on the current knowledge of LAR. (C) 2016 Elsevier Ireland Ltd. All rights reserved.