Akademik Veri Yönetim Sistemi
Polyhedron, cilt.290, 2026 (SCI-Expanded, Scopus)
In this study, the novel mixed ligand Cu(II) complex (H2BPE)[Cu(PDA)2]n, (1) (BPE: 4,4′-ethylenedipyridineethane, H2PDA: 2,3-pyrazinedicarboxylic acid) was obtained under hydrothermal conditions. The complex was defined by using IR, UV–Vis, elemental analysis, magnetic susceptibility techniques, and X-ray crystallography. The coordination geometry revealed that Cu(II) complex has an highly distorted octahedral configuration, coordinated by four carboxylate oxygen atoms and two nitrogen atoms from the PDA2− ligands. The two PDA2− ligands coordinate to the Cu(II) ion through two oxygen and one nitrogen atom, defining the equatorial plane and forming a one-dimensional coordination polymer. In addition, antimicrobial activities of starting materials and 1 against Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Listeria monocytogenes bacteria and Candida albicans yeast were investigated using the microdilution method and compared with existing antibiotics (Cefepime, Vancomycin, Levofloxacin, and Fluconazole). As a result of the activity studies, it was observed that the newly synthesized compounds had activity against bacteria and yeasts. In particular, compound 1 showed better activity against S. aureus (15.60 μg/mL) and C. albicans (31.25 μg/mL) yeast than the control compounds.