Akademik Veri Yönetim Sistemi
Annual Congress of the European Association of Nuclear Medicine (EANM’25), Barcelona, İspanya, 4 - 08 Ekim 2025, cilt.1, ss.475, (Özet Bildiri)
Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) derived from FDG PET/CT have been proposed as prognostic biomarkers in various solid malignancies; however, their prognostic value in laryngeal cancer remains unclear. In this study, we aimed to investigate the relationship between volumetric parameters based on standardized uptake values and overall survival (OS) in newly diagnosed patients with laryngeal squamous cell carcinoma (LSCC) who underwent FDG PET/CT for pre-treatment staging at our department between 2012 and 2020 were retrospectively evaluated. Patients who had not received prior surgery or chemotherapy/radiotherapy and had no additional malignancy were included. SUVmax, SUVmean, MTV, and TLG values of the primary laryngeal lesion were calculated from PET/CT images, and lymphatic and distant metastases were assessed. Clinical, pathological, and demographic data as well as dates of radiological progression and death were obtained from the hospital information system. OS/PFS was analyzed with a 60-month evaluation period.
Results:
A total of 62 patients (58 males, 4 females), aged between 45 and 87 years (mean: 64.75), were included in the study. At the time of analysis, 36 patients had died and 26 were still alive.