NO levels in diabetes mellitus: Effects of L-NAME and insulin on LCAT, Na+/K+ ATPase activity and lipid profile

Tekin N., AKYÜZ F., TEMEL H. E.

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS, cilt.5, sa.4, ss.191-195, 2011 (ESCI, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.dsx.2010.12.004
  • Dergi Adı: DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.191-195
  • Anahtar Kelimeler: Diabetes, Nitric oxide, Na+/K+ ATPase, LCAT, L-NAME, NITRIC-OXIDE, DENSITY-LIPOPROTEIN, OXIDATIVE STRESS, STREPTOZOTOCIN, RATS, ERYTHROCYTE, INHIBITION, METABOLISM, SERUM
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objectives: Diabetes mellitus (DM) is a chronic disease and one of the most important health problems. Several factors may be responsible for the complications of diabetes mellitus including alterations in the activities of sodium-potassium adenosine triphosphatase (Na+/K+ ATPase) and lecithin: cholesterol acyltransferase (LCAT) and also levels of nitric oxide (NO). We have investigated the effects of alterations in serum NO levels on activities of erythrocyte membran Na/K ATPase and serum LCAT enzymes.