Genetic Variation in HIAT1 and IGF1R Genes in Some Goat Populations Reared in Türkiye

Akbulut B., Aktaş Y., Atmaca V., Demir E., Tufan N., Demir E., ...Daha Fazla

Livestock studies, cilt.65, sa.1, ss.8-14, 2025 (Hakemli Dergi)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 1
  • Basım Tarihi: 2025
  • Doi Numarası: 10.46897/livestockstudies.1722830
  • Dergi Adı: Livestock studies
  • Derginin Tarandığı İndeksler: CAB Abstracts, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.8-14
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

This study aimed to assess whether genetic variants of the HIAT1 and IGF1R genes could be integrated into future marker-assisted selection (MAS) studies in three native Turkish

goat populations known as Hair (HAI), Honamlı (HNM), and Kabakulak (KBK) to improve meat traits. In terms of the HIAT1 polymorphism, the frequency of the I allele ranged

from 0.06 (KBK) to 0.35 (HNM), while the D allele frequency ranged from 0.65 (HNM) to 0.94 (KBK). No animals with the II genotype for the HIAT1 gene polymorphism were

identified in KBK goats, while one animal carried this genotype in HAI goats. Regarding the IGFR1 gene polymorphism, the frequency of the A allele ranged from 0.72 (HAI) to

0.92 (HNM), while the T allele frequency varied between 0.08 (HNM) and 0.28 (HAI). Genetic distance-based phylogenetic tree separated HNM goats from KBK and HAI. The

literature pointed out that animals with II and AT genotypes for the HIAT1 and IGF1R genes, respectively, are superior in terms of meat traits. Therefore, this study implies

that the HIAT1 gene is promising for MAS studies in KBK goats, while IGF1R variation could be utilized to improve meat traits in all goat populations in the future.