Association of estrogen receptor alpha and collagen type I alpha 1 gene polymorphisms with bone mineral density in postmenopausal women.

Erdogan, M.; Yildiz, H.; Artan, SEVİLHAN; Solak, M.; Tascioglu, FUNDA; Dundar, U.; Eser, B.; Colak, ERTUĞRUL

doi:10.1007/s00198-010-1312-4

Association of estrogen receptor alpha and collagen type I alpha 1 gene polymorphisms with bone mineral density in postmenopausal women.

Erdogan M. O., Yildiz H., Artan S., Solak M., Tascioglu F., Dundar U., ...Daha Fazla

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, cilt.22, sa.4, ss.1219-25, 2011 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 22 Sayı: 4
Basım Tarihi: 2011
Doi Numarası: 10.1007/s00198-010-1312-4
Dergi Adı: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1219-25
Anahtar Kelimeler: BMD, COL1A1 gene, ER alpha gene, Osteoporosis, Polymorphism, VITAMIN-D-RECEPTOR, BINDING-SITE POLYMORPHISM, OSTEOPOROTIC FRACTURES, DANISH WOMEN, COLIA1 GENE, COL1A1, RISK, EXPRESSION, SEQUENCE, VDR
Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

In this study, ER alpha gene PvuII and XbaI polymorphisms and COL1A1 gene Sp1 polymorphisms in postmenopausal women were compared with lumbar vertebra and femoral neck BMD values. In conclusion, it was designated that PvuII polymorphism was effective on average lumbar vertebra BMD value in postmenopausal women of our study group.