Effect of omentin on cardiovascular functions and gene expressions in isolated rat hearts

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Kutlay O., Kaygisiz Z., Kaygısız B.

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.21, ss.91-97, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21
  • Basım Tarihi: 2019
  • Doi Numarası: 10.14744/anatoljcardiol.2018.52333
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.91-97
  • Anahtar Kelimeler: cyclic GMP, endothelial nitric oxide synthase, heart contractility, L-type Ca2+ channel, omentin, NITRIC-OXIDE SYNTHASE, DOWN-REGULATION, ADIPOSE-TISSUE, AKT, ADIPOCYTOKINE, PHOSPHOINOSITIDE-3-KINASE-GAMMA, IDENTIFICATION, DEPENDENCE, PRESSURE, MYOCYTES
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objective: Omentin is a recently identified novel adipocytokine mainly expressed in the epicardial adipose tissue. Although it has favorable effects on cardiovascular disease, the impact of omentin on the hearts is still an understudied issue. The aim of the present study was to investigate the possible effects of omentin on isolated rat heart.