Assessment of safety and feasibility of non-invasive vagus nerve stimulation for treatment of acute stroke

Arsava, Ethem; Topcuoglu, Mehmet; Ay, Ilknur; Özdemir, ATİLLA; Gungor, Ibrahim; Isikay, Canan; Nazliel, Bijen; Kozak, Hasan; Ozturk, Serefnur; Yilmaz, İbrahim; Dora, Babur; Ay, Hakan; Unal, Ali; Ozel, Tugba; Sorgun, Mine; Bahadır, Eda; Peker, Elif; Aykac, ÖZLEM; Mehdiyev, Zaur; Caglayan, Hale; Gurses, Asli; Pektezel, Mehmet; Yilmaz, Ezgi; Oge, Dogan; Parlak, Safak; Bugrul, Ahmet; Ozguner, Hilal; Seker, Aysu; Ozdemir, Gokhan; Ongun, Gozde; Yilmaz, Sueda; Ozguncu, Cihat; Turan Isik, Saziye; Ildiz, Omer; Mammadli, Azer; Yildogan, Aydin; Mcclure, Candace

doi:10.1016/j.brs.2022.10.012

Assessment of safety and feasibility of non-invasive vagus nerve stimulation for treatment of acute stroke

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Arsava E. M., Topcuoglu M. A., Ay I., Özdemir A. Ö., Gungor I. L., Isikay C. T., ...More

BRAIN STIMULATION, vol.861, no.22, pp.1935-1955, 2022 (SCI-Expanded)

Publication Type: Article / Article
Volume: 861 Issue: 22
Publication Date: 2022
Doi Number: 10.1016/j.brs.2022.10.012
Journal Name: BRAIN STIMULATION
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE, Psycinfo, Directory of Open Access Journals
Page Numbers: pp.1935-1955
Keywords: Acute stroke, Vagus nerve, Stimulation, Safety, Randomized trial, FOCAL CEREBRAL-ISCHEMIA, REDUCES INFARCT SIZE, MIGRAINE, INJURY, TISSUE, MODEL
Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background: Non-invasive vagus nerve stimulation (nVNS) using a hand-held stimulator placed on the neck is an FDA-approved treatment for primary headache disorders. The safety of nVNS is unknown in stroke patients.