JOURNAL OF HAND SURGERY-AMERICAN VOLUME, cilt.51, sa.3, 2026 (SCI-Expanded, Scopus)
Purpose This study used magnetic resonance imaging (MRI) to investigate the effects of forearm pronation and supination on the morphology of the median nerve and carpal tunnel. Materials and Methods The MRI images of 177 patients were analyzed. Median nerve crosssectional area (CSA) and carpal tunnel dimensions (height and width) were measured at four levels in pronation and supination. Statistical analyses evaluated positional differences. Results Median nerve CSA was significantly smaller, carpal tunnel height decreased, and width increased in supination compared with pronation. Pronation caused dorsoradial displacement of the median nerve, whereas supination led to ulnopalmar displacement and superficial positioning relative to flexor tendons. Conclusions The median nerve and carpal tunnel undergo morphological changes during forearm pronation and supination, with supination causing positional shifts, reduced CSA, and increased ovality of the carpal tunnel. Clinical relevance Forearm supination significantly affects carpal tunnel anatomy and morphology, as demonstrated by MRI findings. These findings may serve as a reference for ultrasound-based evaluations and support future efforts to optimize diagnostic and interventional approaches in carpal tunnel syndrome. (J Hand Surg Am. 2026;51(3):289.e1-e7. Copyright (c) 2025 by the American Society for Surgery of the Hand. All rights are reserved, including those for text and data mining, AI training, and similar technologies.)