A Comprehensive Study on Thiadiazole-Based Anticancer Agents Inducing Cell Cycle Arrest and Apoptosis/Necrosis Through Suppression of Akt Activity in Lung Adenocarcinoma and Glioma Cells

AKALIN ÇİFTÇİ, GÜLŞEN; SEVER, BELGİN; ALTINTOP, MEHLİKA

doi:10.4274/tjps.galenos.2019.2018.96658

A Comprehensive Study on Thiadiazole-Based Anticancer Agents Inducing Cell Cycle Arrest and Apoptosis/Necrosis Through Suppression of Akt Activity in Lung Adenocarcinoma and Glioma Cells

AKALIN ÇİFTÇİ G., SEVER B., ALTINTOP M. D.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.16, sa.2, ss.119-131, 2019 (ESCI, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 16 Sayı: 2
Basım Tarihi: 2019
Doi Numarası: 10.4274/tjps.galenos.2019.2018.96658
Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.119-131
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Objectives: Akt is considered as an attractive target for anticancer drug discovery and development and therefore extensive efforts have been devoted to the discovery of new potent anticancer agents targeting Akt.