A Comprehensive Study on Thiadiazole-Based Anticancer Agents Inducing Cell Cycle Arrest and Apoptosis/Necrosis Through Suppression of Akt Activity in Lung Adenocarcinoma and Glioma Cells
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, vol.16, no.2, pp.119-131, 2019 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 16 Issue: 2
- Publication Date: 2019
- Doi Number: 10.4274/tjps.galenos.2019.2018.96658
- Journal Name: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.119-131
- Open Archive Collection: AVESIS Open Access Collection
- Eskisehir Osmangazi University Affiliated: No
Abstract
Objectives: Akt is considered as an attractive target for anticancer drug discovery and development and therefore extensive efforts have been devoted to the discovery of new potent anticancer agents targeting Akt.