Changes of antioxidant enzyme activities during cardiopulmonary bypass

Inal M., Alatas O., Kanbak G., Akyuz F., Sevin B.

JOURNAL OF CARDIOVASCULAR SURGERY, cilt.40, sa.3, ss.373-376, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 3
  • Basım Tarihi: 1999
  • Dergi Adı: JOURNAL OF CARDIOVASCULAR SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.373-376
  • Anahtar Kelimeler: cardiopulmonary bypass, catalase, glutathione peroxidase, glutathione reductase, myocardial ischemia, myocardial reperfusion, RAT-HEART, REPERFUSION, ISCHEMIA, INJURY
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background. Reperfusion of ischemic heart causes the generation of free radicals, and these radicals play an important role in post-ischemic tissue damage. These free radicals are removed by scavenger enzymes and antioxidants in the cell. in this study, erythrocyte catalase, glutathione peroxidase and glutathione reductase enzyme activities were determined in patients undergoing cardiopulmonary bypass.