The relationship of serum uric acid with non-alcoholic fatty liver disease

Sertoglu E., Ercin C. N., Celebi G., Gurel H., KAYADİBİ H., Genc H., ...More

CLINICAL BIOCHEMISTRY, vol.47, no.6, pp.383-388, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 6
  • Publication Date: 2014
  • Doi Number: 10.1016/j.clinbiochem.2014.01.029
  • Journal Name: CLINICAL BIOCHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.383-388
  • Keywords: Non-alcoholic fatty liver disease, Non-alcoholic steatohepatitis, Uric acid, METABOLIC SYNDROME, INSULIN-RESISTANCE, RISK-FACTOR, HYPERURICEMIA, ASSOCIATION, CHOLESTEROL, FEATURES, PLASMA, STROKE
  • Eskisehir Osmangazi University Affiliated: No

Abstract

Objectives: Non-alcoholic fatty liver disease (NAFLD) is a clinicopathological entity which is characterized by the presence of fat droplets in hepatocytes without alcohol consumption, representing a spectrum of hepatic injuries, ranging from simple steatosis (SS) to non-alcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. In recent years, experimental and observational studies suggest a role for serum uric acid (SUA) in NAFLD. However, there are few reports investigating SUA in histologically proven NAFLD. The aim of the present study was to evaluate the relationship of SUA with liver histology in non-diabetic patients with NAFLD.