The relationship of serum uric acid with non-alcoholic fatty liver disease

Sertoglu E., Ercin C. N., Celebi G., Gurel H., KAYADİBİ H., Genc H., ...Daha Fazla

CLINICAL BIOCHEMISTRY, cilt.47, sa.6, ss.383-388, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.clinbiochem.2014.01.029
  • Dergi Adı: CLINICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.383-388
  • Anahtar Kelimeler: Non-alcoholic fatty liver disease, Non-alcoholic steatohepatitis, Uric acid, METABOLIC SYNDROME, INSULIN-RESISTANCE, RISK-FACTOR, HYPERURICEMIA, ASSOCIATION, CHOLESTEROL, FEATURES, PLASMA, STROKE
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Objectives: Non-alcoholic fatty liver disease (NAFLD) is a clinicopathological entity which is characterized by the presence of fat droplets in hepatocytes without alcohol consumption, representing a spectrum of hepatic injuries, ranging from simple steatosis (SS) to non-alcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. In recent years, experimental and observational studies suggest a role for serum uric acid (SUA) in NAFLD. However, there are few reports investigating SUA in histologically proven NAFLD. The aim of the present study was to evaluate the relationship of SUA with liver histology in non-diabetic patients with NAFLD.