Intraspecific Variability in the Gray Oyster Culinary-Medicinal Mushroom Pleurotus ostreatus (Agaricomycetes): Glucan, Ergothioneine, and Lovastatin Profiles with Biological Implications
International Journal of Medicinal Mushrooms, cilt.28, sa.10, ss.61-77, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 10
- Basım Tarihi: 2026
- Doi Numarası: 10.1615/intjmedmushrooms.2026066509
- Dergi Adı: International Journal of Medicinal Mushrooms
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
- Sayfa Sayıları: ss.61-77
- Anahtar Kelimeler: bottle culture, ergothioneine, glucan, lovastatin, medicinal mushrooms, Pleurotus ostreatus
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
Pleurotus ostreatus is a well-known culinary-medicinal mushroom for its rich nutritional composition and diverse biological activities. The present study aimed to comparatively evaluate 115 wild isolates and five commercial strains cultivated under controlled bottle-culture conditions in terms of β-glucan, ergothioneine, and lovastatin contents, as well as selected biological activities and nutritional parameters. Isolates PO85, PO71, and PO36 exhibited the highest β-glucan [61.526 g/100 g dry weight (dw)], lovastatin (1.509 mg/g dw), and ergothioneine (10.732 mg/g dw) contents, respectively. In biological activity assays, the isolate PO85 promoted the growth of Lactobacillus strains effectively, lovastatin-rich extract of isolate PO116 pronounced antifungal activity against Candida albicans, and ergothioneine-rich extract of isolate PO164 exhibited the highest antioxidant capacity in the ABTS radical scavenging assay. In terms of nutritional analysis, isolate PO71 was rich in dry matter, nitrogen, and protein, whereas isolate PO85 had high moisture, ash, and reducing sugar levels but lower fat content. These findings highlight the significant intraspecific variability of P. ostreatus and suggest that some isolates may offer potential for future functional food applications due to their metabolite profiles and biological activities.