Turk Beyin Damar Hastaliklar Dergisi, vol.17, no.2, pp.55-61, 2011 (Scopus)
AIM: We aimed to investigate whether there is an association between blood flow parameters of middle cerebral artery measured with transcranial Doppler which is an easy, low-cost, noninvasive, repeatable and bedside applicable examination and prognosis during acute, subacute and chronic periods in patients with acute ischemia on middle cerebral artery territory. MATERIALS AND METHODS: Twenty-six patients with acute ischemia on middle cerebral artery territory, applied within first 12 hours after start of symptom and meet the study criteria were included. The middle cerebral artery blood flow parameters were measured with transcranial Doppler during acute period. Also, stroke severity and prognosis were determined on detailed neurologic examination with GCS, NIHSS and mRANKIN values during acute, subacute and chronic periods. Data of 26 patients were analyzed in this study. RESULTS: Transcranial Doppler was performed within mean 6.0±2.9 hours during acute period. When we look at blood flow velocity parameters with transcranial Doppler during acute period, pulsatility index on the lesion side was 1.5±0.8. Based on the detailed neurologic examination during acute period, mean arrival GCS was 13.2±2.4 and mean arrival NIHSS was 10.9±6.3. Mean NIHSS and mRS were found 11.5±10.1 and 3.1±2.0 on neurological examination during subacute period, respectively. Mean NIHSS and mRS were found 9.9±12.2 and 2.4±2.4 on neurological examination during chronic period, respectively. There were significantly negative association between pulsatility index measured at the side of lesion during acute period and arrival GCS (p=0.009) and significantly positive association between pulsatility index and arrival NIHSS (p=0.001). In addition, significant positive associations were found between the pulsatility index on the side of lesion during acute period with NIHSS (p=0,009 ve p=0,013, respectively) and mRANKIN (P=0,035 ve p=0,049, respectively) values measured during subacute and chronic periods. CONCLUSION: In this study, we concluded that important information about prognosis on acute, subacute and chronic periods can be obtained with pulsatility index measurement which is not affected by measuring fondness among the blood flow parameters measured with transcranial Doppler that as a simple examination method on acute stroke.