A new approach to an old hypothesis; phototherapy does not affect ductal patency via PGE(2) and PGI(2)

Surmeli-Onay Ö., YURDAKÖK M., KARAGÖZ T., Erkekoglu P., ERTUĞRUL İ., Takci S., ...More

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, vol.28, no.1, pp.16-22, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.3109/14767058.2014.899575
  • Journal Name: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.16-22
  • Keywords: Patent ductus arteriosus, preterm infant, phototherapy, prostaglandin, GESTATIONAL-AGE, PRETERM INFANTS, OXYGEN-TENSION, SMOOTH-MUSCLE, ARTERIOSUS, PROSTAGLANDIN, RELAXATION, LIGHT
  • Eskisehir Osmangazi University Affiliated: No

Abstract

Objective: Numerous investigations have demonstrated that phototherapy (PT) directly or indirectly causes ductal patency by photorelaxation effect. In this observational study, we aimed to assess the effect of PT on the incidence of patent ductus arteriosus (PDA) together with prostaglandins (PGE(2)) and (PGI(2)) levels in preterm infants.