Successful Treatment of MuSK Antibody-Positive Myasthenia Gravis with Rituximab


Sen A. D. Y., BAYSAL A., Aydin O. U., ÇARMAN K. B., YARAR C.

JOURNAL OF CHILD - COCUK DERGISI, vol.25, no.3, pp.172-175, 2025 (ESCI, TRDizin)

  • Publication Type: Article / Article
  • Volume: 25 Issue: 3
  • Publication Date: 2025
  • Doi Number: 10.26650/jchild.2025.1704940
  • Journal Name: JOURNAL OF CHILD - COCUK DERGISI
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.172-175
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Muscle-specific tyrosine kinase antibody-associated myasthenia gravis (MuSK-MG) is a rare subtype of MG distinguished by recurring relapses and a clinical history unresponsive to conventional therapies. Rituximab, a monoclonal antibody that targets CD20+ B cells, has effectively induced long-term remission in adults. We report a pediatric MuSK-MG patient who exhibited a favourable response to rituximab following the ineffectiveness of steroid therapy and acetylcholinesterase inhibitor (AChEI) therapy.