Akademik Veri Yönetim Sistemi
World Interventional Neurology and Neurosurgery Congress (WINNC), İstanbul, Türkiye, 1 - 03 Ekim 2025, ss.14, (Özet Bildiri)
Introduction
Cavernous malformations are clusters of hyalinized capillaries separated by sinusoidal vascular channels, notably lacking intervening brain parenchyma. Their incidence is es]mated at 0.4–0.8%. They are typically diagnosed in adolescence or middle age, with approximately 75% located supratentorially, most oken in the frontal and temporal lobes. This study aimed to investigate the clinical course and radiological features of cavernous malformations in our cohort, classified according to the Zabramski system.
Materials and Methods
A retrospective cohort of 96 pa]ents diagnosed with cavernous malformations between 2015 and 2025 was analyzed. Pa]ents were classified based on MRI findings according to the Zabramski classification. Clinical presenta]on and neurological examination findings at admission were also assessed.
Results
The mean age at diagnosis was 42 years. Cavernous malformations were supratentorial in 75% of cases (most commonly frontal and temporal), and infratentorial in 25%. According to Zabramski classification, 29 pa]ents had type I, 41 had type II, 16 had type III, and 7 had type IV lesions. During follow-up, three patients demonstrated transformation from type II to type I.
• Treatment: 26 patients (27%) underwent surgery immediately aker diagnosis; 61 patients (63.5%) were managed conserva]vely; 6 patients (6.3%) received Gamma Knife radiosurgery. Additionally, three patients with type II lesions that progressed to type I underwent surgery during follow-up.
• Neurological status: All patients with type IV lesions showed no deficits and were followed conservatively. The highest rate of neurological deficits was observed in type I lesions. Among 44 pa]ents with type II lesions, 3 (6.82%) transformed into type I.
• Symptoms: The most frequent presenting complaints were headache and seizures.
Conclusion
In our series, the majority of patients requiring surgery had Zabramski type I and type II lesions. These findings highlight the usefulness of the Zabramski classification in guiding follow-up strategies and treatment planning for patients with cavernous malformations.