Cord blood IGF-1 and IGFBP-3 levels in asphyxiated term newborns


DİNLEYİCİ E. Ç., Tekin N., Colak O., Aksit M. A.

NEUROENDOCRINOLOGY LETTERS, vol.27, no.6, pp.745-747, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 6
  • Publication Date: 2006
  • Journal Name: NEUROENDOCRINOLOGY LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.745-747
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

OBJECTIVE: Determination and pathogenesis of perinatal asphyxia is still an important problem. During the asphyxial insult and recovery phase, alteration of the growth factors has been demonstrated and there is evidence that expression of insulin-like growth factors (IGF) and their insulin-like growth factor binding proteins (IGFBP) in injured sites in experimental studies. Aim of this study was to evaluate relationship between serum IGF-1, IGFBP-3 levels and perinatal asphyxia.