ANESTHESIA INDUCTION WITH SEVOFLURANE AND PROPOFOL: EVALUATION OF P-WAVE DISPERSION, QT AND CORRECTED QT INTERVALS

Hanci V., Aydin M., Yurtlu B. S., Ayoglu H., Okyay R. D., Tas E., ...Daha Fazla

KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, cilt.26, sa.9, ss.470-477, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 9
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/s1607-551x(10)70074-7
  • Dergi Adı: KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.470-477
  • Anahtar Kelimeler: anesthesia induction, P-wave dispersion, propofol, QT interval, sevoflurane, ARTERY-BYPASS-SURGERY, ATRIAL-FIBRILLATION, SUPRAVENTRICULAR TACHYCARDIA, DIABETES-MELLITUS, OBESE SUBJECTS, DE-POINTES, HEART-RATE, CHILDREN, REPOLARIZATION, PROTECTION
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

The present study compared the effects of anesthesia induction with sevoflurane and propofol on hemodynamics, P-wave dispersion (Pwd), QT interval and corrected QT (QTc) interval. A total of 72 adult patients were included in this prospective study. All patients had control electrocardiograms (ECGs) before anesthesia induction. Anesthesia was induced with sevoflurane inhalation or intravenous propofol. Electrocardiography for all patients was performed during the 1(St) and 3(rd) minutes of induction, 3 minutes after administration of muscle relaxant, and at 5 minutes and 10 minutes after intubation. Pwd and QT intervals were measured on all ECGs. QTc intervals were determined using the Bazett formula. There was no significant difference in Pwd and QT and QTc intervals on control ECGs. in the sevoflurane group, except for control ECGs, Pwd and QTc interval on all ECGs were significantly longer than those in the propofol group (p<0.05). We conclude that propofol should be used for anesthesia induction in patients with a predisposition to preoperative arrhythmias, and in those whose Pwd and QTc durations are prolonged on preoperative ECGs.