No Interaction Between Childhood Maltreatment and Serotonin Transporter Gene in Recurrent Major Depressive Disorder: A Clinical Sample

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Ozcurumez G., Yurdakul H. T., Terzi Y., Direk N., Essizoglu A., Sahin F.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.56, sa.2, ss.110-114, 2019 (SCI-Expanded, Scopus, TRDizin)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 56 Sayı: 2
• Basım Tarihi: 2019
• Doi Numarası: 10.29399/npa.23325
• Dergi Adı: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.110-114
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Introduction: There is inconsistent evidence of interaction between childhood adversities and a serotonin transporter promoter polymorphism (5- HTTLPR) in depression. It is hypothesized that genetic sensitivity to stress could be more specific to recurrent major depressive disorder (MDD). The aim of the study is to replicate a recent study which provided preliminary evidence of interaction between severity of childhood maltreatment and the 5-HTTLPR polymorphism in recurrent MDD.