Morinda Citrifolia (Noni) and Low Dose Aspirin Prevent Apoptotic Cell Death and Oxidative Stress on Isoproterenol Induced Myocardial Infarction in Rats

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Ol K. K., KANBAK G., Ilhan A. O., Kartkaya K., Inal M. E.

ERCIYES MEDICAL JOURNAL, cilt.39, sa.4, ss.165-170, 2017 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/etd.2017.1732
  • Dergi Adı: ERCIYES MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.165-170
  • Anahtar Kelimeler: Aspirin, cathepsin B, caspase-3, catalase, Morinda citrifolia (noni), SOD, CHEMICAL-CONSTITUENTS, LIPID PEROXIDES, ACID, ISCHEMIA, ANTIOXIDANTS, INHIBITION, DAMAGE, DYSFUNCTION, OXIDANTS, LIVER
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objective: Isoproterenol (iso)-induced myocardial infarction is a widely used experimental model to study the beneficial effects of many drugs. Morinda citrifolia (noni) has traditionally been used for treating many diseases. Low-dose aspirin may have been protected heart tissueThis study aimed to investigate the possible protective effects of noni (20%) and low-dose aspirin (30 mg/kg) against iso-induced acute myocardial infarction in male Wistar rats.