Probing chromosome structure with dynamic force relaxation
Physical Review Letters, cilt.86, sa.2, ss.360-363, 2001 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 86 Sayı: 2
- Basım Tarihi: 2001
- Doi Numarası: 10.1103/physrevlett.86.360
- Dergi Adı: Physical Review Letters
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.360-363
- Eskişehir Osmangazi Üniversitesi Adresli: Hayır
Özet
Chromosomes from new epithelial cells (TVI cell line) grown in a monolayer on a small dish were microdissected. The dynamics of stress relaxation in the microdissected chromosomes was characterized. It was found that mitotic chromosomes quickly stretched display well-defined elastic response with a relaxation time on the second time scale. Further, it was observed that loose loop domains are present in physiological conditions.