The therapeutic potential of amifostine on cyclophosphamide-induced testicular dysfunction in rats: An experimental study
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE, cilt.17, sa.4, ss.245-252, 2019 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 17 Sayı: 4
- Basım Tarihi: 2019
- Doi Numarası: 10.18502/2
- Dergi Adı: INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Sayfa Sayıları: ss.245-252
- Anahtar Kelimeler: Amifostine, Cyclophosphamide, Rat, Testis, TESTIS, DOXORUBICIN, PROTECTS, INJURY, ACID, DRUG
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
Background: Cyclophosphamide (CP) is a well-known alkylating anticancer agent used in the treatment of various malignant and non-malignant tumors. CP may also cause a variety of adverse effects, including reproductive toxicity. Amifostine is known as a cytoprotective drug having antioxidant properties.