Torticollis in a haemophilic infant with inhibitor: a case of spinal epidural haematoma


Oymak Y., Muminoglu N., Ay Y., Karapinar T. H. , Koker S. A. , Toret E. , ...Daha Fazla

BLOOD COAGULATION & FIBRINOLYSIS, cilt.27, sa.5, ss.576-579, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1097/mbc.0000000000000465
  • Dergi Adı: BLOOD COAGULATION & FIBRINOLYSIS
  • Sayfa Sayıları: ss.576-579

Özet

Central nervous system bleeding, which can be a life-threatening complication, is seen in 2.7% of patients with haemophilia. Spinal epidural haematomas represent about one-tenth of such cases. Here, we report on a 10-month-old boy with severe haemophilia A, who presented with torticollis. Although administration of factor VIII at a dose of 50 U/kg, the patient developed flaccid paralysis of the upper extremities. Factor VIII inhibitor screen was positive. Magnetic resonance imaging of the spine revealed spinal epidural haematomas, extending from C-1 to the cauda equina. Treatment was continued with recombinant activated factor VIIa without surgery. After 1 month, complete neurological recovery was achieved and fully resolved haematomas were detected on spinal MRI. A prompt radiological evaluation of the cervical spine with MRI should be made in patients with haemophilia presenting with torticollis. In addition, in the case of life-threatening bleeding in patients with haemophilia, the possibility of an inhibitor should be kept in mind. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.