Prognostic value of D-dimer/fibrinogen ratio on in-hospital outcomes of patients with heart failure and COVID-19.

Murat S., Murat B., Dural M., Mert G. Ö., Cavusoglu Y.

Biomarkers in medicine, cilt.15, sa.16, ss.1519-1528, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 16
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2217/bmm-2021-0341
  • Dergi Adı: Biomarkers in medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1519-1528
  • Anahtar Kelimeler: coronavirus disease, D-dimer, fibrinogen ratio, heart failure, D-DIMER, PULMONARY-EMBOLISM, THROMBOEMBOLISM, GUIDELINES, DIAGNOSIS, ACCURACY
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Aim: In the present study, the relationship between D-dimer/fibrinogen ratio (DFR) and in-hospital outcomes was evaluated in patients with COVID-19 and a diagnosis of heart failure (HF). Materials & methods: In-hospital outcomes were compared in patients with high and low DFR values. Results: With regard to in-hospital outcomes, patients in the third tertile of DFR had a higher rate of mechanical ventilation, cardiogenic shock and death (p < 0.001). The length of ICU stay was longer in the third tertile group (p < 0.001). When evaluated together with infection markers, DFR was found to be an independent predictor of outcomes. Conclusion: DFR can be used as a prognostic marker in patients with COVID-19 with a diagnosis of HF, and perhaps more valuable than other infection markers.