Detection of deletions and/or amplifications of genes related with lung cancer by multiplex ligation-dependent probe amplification (MLPA) technique

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Tepeli E., Muslumanoglu M. H., Uludag A., Buyukpinarbasili N., Ozdemir M., Oznur M., ...Daha Fazla

CANCER BIOLOGY & THERAPY, cilt.8, sa.22, ss.2160-2164, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 22
  • Basım Tarihi: 2009
  • Doi Numarası: 10.4161/cbt.8.22.9840
  • Dergi Adı: CANCER BIOLOGY & THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2160-2164
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Background: Lung cancer has the leading mortality rate among all cancers and it is the second most common cause of death following cardiovascular diseases. The aim of the study was determining deleted and/or amplified regions of 64 different loci previously associated with lung cancer, by using Multiplex Ligation-dependent Probe Amplification (MLPA).