JOURNAL OF ACADEMIC RESEARCH IN MEDICINE-JAREM, cilt.8, sa.2, ss.59-62, 2018 (ESCI)
Objective: The mortality rate is high for severe sepsis and septic shock. Presently, there are no specific treatments that can reduce mortality in patients with sepsis and multiple organ dysfunction. Therapeutic plasma exchange (TPE) is the automatic separation of a patient's plasma using medical devices and its replacement with healthy donor plasma. TPE may be beneficial in selected cases, even though not routinely recommended by international sepsis guidelines.