Human Mastadenovirus A Infection in a Child During the Course of Hematopoietic Stem Cell Transplant
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, cilt.22, sa.9, ss.726-729, 2024 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22 Sayı: 9
- Basım Tarihi: 2024
- Doi Numarası: 10.6002/ect.2022.0049
- Dergi Adı: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.726-729
- Eskişehir Osmangazi Üniversitesi Adresli: Evet
Özet
Following primary infection, human mastadenoviruses can persist in various tissues. We report a case of a pediatric patient with Fanconi anemia who had a complicated posttransplant course after allogeneic hematopoietic stem cell transplant that was associated with human mastadenovirus infection. Human mastadenovirus reactivation was detected with metagenomic analysis during a 3-month followup period; the predominant rate of occurrence of human mastadenoviruses was 1.1% on day 0, 84% on day +15, 90% on day +30, and 42% on day +82. Virus shedding continued up to 3 months after transplant. At 36 months after hematopoietic stem celltransplant, the patient was in good clinical condition with full donor chimerism. Long-term follow-up studies for human mastadenoviruses are needed to determine latency period.