Antiproliferative and antiapoptotic effect of thymoquinone on cancer cells in vitro

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Kus G., Ozkurt M., Kabadere S., Erkasap N., Goger G., Demirci F.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.119, no.5, pp.312-316, 2018 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 119 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.4149/bll_2018_059
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.312-316
  • Keywords: thymoquinone, in vitro, apoptosis, antiproliferative, anticancer, SATIVA SEED OIL, NIGELLA-SATIVA, APOPTOSIS, PROLIFERATION, ACTIVATION, STRESS, GROWTH, MODEL, LINE
  • Open Archive Collection: AVESIS Open Access Collection
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

OBJECTIVES: Nigella sativa oil and thymoquinone were comparatively tested in vitro for their effects on human cancer cell lines (glioma, T98; prostate, LnCaP) as well as mouse embryonic fi broblast cell lines (3T3), and for the induction of apoptosis.