Antiproliferative and antiapoptotic effect of thymoquinone on cancer cells in vitro

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Kus G., Ozkurt M., Kabadere S., Erkasap N., Goger G., Demirci F.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.119, sa.5, ss.312-316, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 119 Sayı: 5
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4149/bll_2018_059
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.312-316
  • Anahtar Kelimeler: thymoquinone, in vitro, apoptosis, antiproliferative, anticancer, SATIVA SEED OIL, NIGELLA-SATIVA, APOPTOSIS, PROLIFERATION, ACTIVATION, STRESS, GROWTH, MODEL, LINE
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

OBJECTIVES: Nigella sativa oil and thymoquinone were comparatively tested in vitro for their effects on human cancer cell lines (glioma, T98; prostate, LnCaP) as well as mouse embryonic fi broblast cell lines (3T3), and for the induction of apoptosis.