Evaluation of Effects of Quercetin (3, 3 ', 4 ', 5, 7-pentohidroxyflavon) on Apoptosis and Telomerase Enzyme Activity in MCF-7 and NIH-3T3 Cell Lines Compared with Tamoxifen

AK CAN, AYŞE; Basaran, Ayse; DİKMEN, MİRİŞ; TURGUT COŞAN, DİDEM; DEĞİRMENCİ, İRFAN; Gunes, Hasan

doi:10.5174/tutfd.2010.03372.3

Evaluation of Effects of Quercetin (3, 3 ', 4 ', 5, 7-pentohidroxyflavon) on Apoptosis and Telomerase Enzyme Activity in MCF-7 and NIH-3T3 Cell Lines Compared with Tamoxifen

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AK CAN A., Basaran A., DİKMEN M., TURGUT COŞAN D., DEĞİRMENCİ İ., Gunes H. V.

BALKAN MEDICAL JOURNAL, vol.28, no.3, pp.293-299, 2011 (SCI-Expanded)

Publication Type: Article / Article
Volume: 28 Issue: 3
Publication Date: 2011
Doi Number: 10.5174/tutfd.2010.03372.3
Journal Name: BALKAN MEDICAL JOURNAL
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.293-299
Eskisehir Osmangazi University Affiliated: Yes

Abstract

Objective: Quercetin has been shown to inhibit the proliferation of cancer cells. Tamoxifen is used for breast cancer. In this study, we have aimed to investigate the effects of quercetin and tamoxifen on telomerase enzyme activity and apoptosis in two cell lines.