Effects of Gabapentin on Carrageenan-Induced Inflammation, Acute Phase Reactants and Gastric Mucus Secretion in Rats

Kılıç F. S., Aydın Ş., Yildirim C., Donertas B., Oner S., Kaygısız B.

EUROPEAN JOURNAL OF THERAPEUTICS, cilt.25, ss.23-27, 2019 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/eurjther.2018.543
  • Dergi Adı: EUROPEAN JOURNAL OF THERAPEUTICS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.23-27
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objective: Gabapentin (GBP), which was first developed as an anticonvulsant agent, has recently gained great attention considering its pain relieving and anti-inflammatory effects. The aim of the present study was to investigate the anti-inflammatory effect of GBP on carrageenan (CAR)-induced paw edema and its gastric side effects by determining gastric mucus secretion in rats.