SCREENING FOR FUNCTIONAL GASTROINTESTINAL DISORDERS IN PRETERM INFANTS UP TO 12 MONTHS OF CORRECTED AGE: A PROSPECTIVE COHORT STUDY

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Aydemir Y., Aydemir Ö., Dinleyici M., Çakıl Sağlık A., Barsan Kaya T., Cam D., ...Daha Fazla

ESPGHAN 55. ANNUAL MEETİNG, Vienna, Avusturya, 17 - 20 Mayıs 2023, ss.62-63

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Vienna
  • Basıldığı Ülke: Avusturya
  • Sayfa Sayıları: ss.62-63
  • Eskişehir Osmangazi Üniversitesi Adresli: Evet

Özet

Objectives and Study: Functional gastrointestinal disorders (FGIDs) in infants are characterized by a variety of symptoms that are frequently age-dependent, chronic, or recurrent and are not explained by structural or biochemical abnormalities. There are studies in the literature reporting different results regarding the relationship between prematurity and FGIDs. The main objective of this study was to compare the frequency of FGIDs between preterm and term born infants. The secondary objective was to evaluate whether there was any association between feeding type during infancy and development of FGIDs. Methods: A multicentre prospective cohort study that included preterm infants born before 37 weeks of gestation and healthy term infants was carried out. At 1, 2, 4, 6, 9, and 12 months of age, infants were assessed for the presence of FGIDs using the Rome IV criteria. In preterm born infants, an additional follow-up visit was made at 12 months corrected age. Results: 134 preterm and 104 term infants were enrolled in the study. Infantile colic, rumination syndrome, functional constipation, and infant dyschezia were more common in preterm infants. Incidence of other FGIDs (infant regurgitation, functional diarrhoea and cyclic vomiting syndrome) were similar among preterm and term born infants (Table). Exclusively breastfeed preterm infants in the first 6 months of life have a lower incidence of infantile colic (18.8% vs 52.1%, p=0.025). In terms of chronological age, FGIDs symptoms started later in preterm born infants; this difference was statistically significant for infantile colic and regurgitation (median age 2 months vs 1 month, p<0.001). Downloaded from http://journals.lww.com/jpgn by BhDMf5ePHKav1zEoum1tQfN4a+kJLhEZgbsIHo4XMi0hCywCX1AW nYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC1y0abggQZXdtwnfKZBYtws= on 07/06/2023 Volume 76, Supplement 1, June 2023 DOI 10.1097/MPG.0000000000003823 63 Conclusions: Prematurely born infants have a higher prevalence of FGIDs compared with term born controls. Therefore, especially if they have gastrointestinal complaints, they should be screened for FGIDs. Possibly due to maturational differences, the time of occurrence of FGIDs may differ in preterm infants. Infantile colic incidence decreases with exclusive breastfeeding.