The interactions of cephalosporins on polyol pathway enzymes from sheep kidney

ŞENGÜL, BÜLENT; BEYDEMİR, ŞÜKRÜ

doi:10.1080/13813455.2017.1358749

The interactions of cephalosporins on polyol pathway enzymes from sheep kidney

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ŞENGÜL B., BEYDEMİR Ş.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY, vol.124, no.1, pp.35-44, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 124 Issue: 1
Publication Date: 2018
Doi Number: 10.1080/13813455.2017.1358749
Journal Name: ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.35-44
Eskisehir Osmangazi University Affiliated: No

Abstract

Context: Cephalosporins are derived from the fungus Acremonium. Due to their strong bactericidal ability, these drugs have to a wide usage in medicine.Objective: An investigation of the effects on sheep renal aldose reductase (AR) and sorbitol dehydrogenase (SDH) of cefoperazone, cefazolin, cefuroxime, ceftazidime and ceftriaxone as cephalosporin drugs was carried out in the present study.