The relation between brain MRI findings and blood manganese levels in renal transplantation, hemodialysis, and peritoneal dialysis patients

Akcan E., ÖZKURT S., ŞAHİN G., YALÇIN A. U., Adapinar B.

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.50, no.1, pp.173-177, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.1007/s11255-017-1731-7
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.173-177
  • Keywords: Hemodialysis, Peritoneal dialysis, Renal transplantation, Manganese, Pallidal index, LONG-TERM CHANGES, TRACE-ELEMENTS, HEPATIC-ENCEPHALOPATHY, BASAL GANGLIA, HIGH SIGNAL, IMAGES, INTENSITY, EXCRETION, LIVER, ZINC
  • Eskisehir Osmangazi University Affiliated: Yes


Various factors can affect blood and tissue levels of trace elements in patients with end-stage renal disease. There are a few studies showing hyperintensity of basal ganglia associated with manganese deposition in hemodialysis (HD) patients. The present study aimed to investigate the intensity changes as markers of manganese deposition in the basal ganglia and to demonstrate their association with blood manganese levels using ICP/MS technique in HD, peritoneal dialysis (PD), and renal transplant patients.