Hypertonic saline injection in the treatment of rectal prolapsus: An experimental and clinical study

Taneli C., Ilhan H., Ozcan C., Tuncyurek M., Balik E.

Pediatrik Cerrahi Dergisi, vol.7, no.2-3, pp.63-65, 1993 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 2-3
  • Publication Date: 1993
  • Journal Name: Pediatrik Cerrahi Dergisi
  • Journal Indexes: Scopus
  • Page Numbers: pp.63-65
  • Keywords: Hypertonic saline, Rectal prolapsus
  • Eskisehir Osmangazi University Affiliated: Yes


Hypertonic saline injection is one of the methods used for the treatment of rectal prolapsus. Saline solution in 30% has been frequently preferred. Severe inflammatory reaction and perirectal abscess formation are the complications most often encountered. To identify the ideal concentration of the perirectally injected hypertonic saline, 28 rabbits were put into 4 groups and were given injections of a single dose of either 5, 10 or 30% of saline solutions to the study group and isotonic saline to the control group. After a period of 4 weeks the anorectal segments were extirpated and studied histopathologically in view of perirectal fibrosis. Fibrosis was encountered in all groups but was most pronounced in the group injected 30% saline. Post injection complications were seen only in the group of 30% saline injections. Following the present experimental study a clinical study was started this time in 14 patients with rectal prolapsus. In 7 of the study group 5% saline injections, in 7 of them 10% saline injections were performed. In conclusion; 5% saline injections were found ineffective. Although 30% saline injections were effective enough, the risk of complication was high. Whereas in the group of 10% injections the concentration of saline was effective to form an adequate amount of fibrosis without any risk of complication.