Erythropoietin Improves the Healing of Skin Necrosis Resulting From Doxorubicin Extravasation in a Rat Model


Bilge N. S. Y. , DÜNDAR E., MUTLU F., Gulbas Z.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, vol.72, no.4, pp.141-149, 2011 (SCI-Expanded) identifier identifier identifier

Abstract

BACKGROUND: Doxorubicin is an antineoplastic agent that causes skin necrosis when extravasated. Various agents have been tried to reduce tissue damage owing to extravasation. Erythropoietin (EPO) is an obligatory growth factor for red blood cells and has beneficial effects on wound healing.