Increased intraabdominal pressure impairs liver regeneration after partial hepatectomy in rats

Kaya Y., Aral E., Coskun T., Erkasap N., Var A.

JOURNAL OF SURGICAL RESEARCH, vol.108, no.2, pp.250-257, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 108 Issue: 2
  • Publication Date: 2002
  • Doi Number: 10.1006/jsre.2002.6555
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.250-257
  • Eskisehir Osmangazi University Affiliated: Yes

Abstract

Background. There are many experimental studies showing that increased intraabdominal pressure (LAP) reduces liver blood flow, leading to ischemia and portal venous congestion. But, there is no study evaluating the effect of increased IAP on liver regeneration. It is well known that acute liver ischemia and portal venous congestion impair liver regeneration. We, therefore, aimed to determine the effect of increased LAP on liver regeneration in this study.