In vitro and in silico studies on AChE inhibitory effects of a series of donepezil-like arylidene indanones

SEVER B., ALTINTOP M. D., TEMEL H. E.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.45, sa.4, ss.359-363, 2020 (SCI-Expanded, Scopus, TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1515/tjb-2019-0356
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.359-363
  • Eskişehir Osmangazi Üniversitesi Adresli: Hayır

Özet

Objective: Donepezil is the most potent acetylcholinesterase (AChE) inhibitor currently available on the market for the management of Alzheimer's disease. In this study, it was aimed to identify potent donepezil analogues.